Changes
/* Test Results */
|align = "center"|5
|align = "center"|0.60 ± 0.03
|}
{|border="2" cellspacing="0" cellpadding="4" width="62%"
|align = "center" bgcolor = "#9BBB59" colspan = "6"|'''A)Intrinsic clearance CLi, mL/min/g liver'''
|-
|align = "center"|
|align = "center" bgcolor = "#4F81BD"|'''Mouse'''
|align = "center" bgcolor = "#4F81BD"|'''Rat'''
|align = "center" bgcolor = "#4F81BD"|'''Dog'''
|align = "center" bgcolor = "#4F81BD"|'''Monkey'''
|align = "center" bgcolor = "#4F81BD"|'''Human'''
|-
|align = "center" bgcolor = "#4F81BD"|'''Microsomes'''
|align = "center"|0.7
|align = "center"|<nowiki><</nowiki>0.5
|align = "center"|<nowiki><</nowiki>0.5
|align = "center"|<nowiki><</nowiki>0.5
|align = "center"|<nowiki><</nowiki>0.5
|-
|align = "center" bgcolor = "#4F81BD"|'''Hepatocytes'''
|align = "center"|<nowiki><</nowiki>0.5
|align = "center"|3.7
|align = "center"|1.7
|align = "center"|<nowiki><</nowiki>0.5
|align = "center"|<nowiki><</nowiki>0.5
|-
|align = "center" bgcolor = "#9BBB59" colspan = "6"|'''B)CYP450 Inhibition IC50 µM'''
|-
|align = "center"|
|align = "center"|3A4
|align = "center"|1A2
|align = "center"|2D6
|align = "center"|2C9
|align = "center"|2C19
|-
|align = "center"|
|align = "center"|<nowiki>></nowiki>33
|align = "center"|<nowiki>></nowiki>33
|align = "center"|3.0 ± 1.8
|align = "center"|<nowiki>></nowiki>33
|align = "center"|<nowiki>></nowiki>33
|}