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/* Summary */
'''Toxicology studies'''
*Maximum tolerated dose 100 mg/kg (oral; dog) and 300 mg/kg (oral; rat)*Dose-limiting toxicity at 300 mg/kg (orally; dog)
*Few toxic signs in expected therapeutic range
*Toxicology studies established target organ(s)which are similar to other drugs in class: kidney and possibly hematologic system
*Toxicology studies paired with pharmacology data show acceptable margin of safety